Magnesium Trisilicate IP
CAS No. : 14987-04-3 Molecular Formula : Mg2Si3O8,xH2O Category : Antacid Storage Condition : Store protected from moistureSource : IP-2010 Vol-2, Page No.1626
Grades: I.P./B.P./U.S.P.
Application:
It is used as Anti-adherent and Lubricant in Tablet manufacturing and in Antacid tablets and suspensions formulations.
Specifications:
Test Parameters |
Specification / Limits |
Description | Fine white powder, free from grittiness odorless, slightly hygroscopic |
Solubility | Practically insoluble in water and in ethanol 95 % |
Alkalinity | Complies as I.P./B.P./U.S.P. |
Arsenic | Not more than 4 ppm |
Heavy Metals | Not more than 30 ppm |
Chloride | Note more than 500 ppm |
Sulphate | Not more than 0.5% ppm |
Acid absorption | Not less than 100 ml. of 0.1m Hydrochloric acid required to neutralize 1.0 gm. |
Water soluble salts | Not more than 30 mg per Gm. |
Loss on Ignition | Not less than 17.0% & not more than 34.0% |
Assay As %Mgo | Not less than 29.0% |
Assay As %Sio | Not less than 65.0 |
Magnesium Trisilicate USP
CAS No. : 14987-04-3 Molecular Formula : Mg2Si3O8,xH2O Molecular Weight : 260.86 gm/mol Storage Condition : Preserve in tight containerSource : USP-34, Page No. 3371
Grades: I.P./B.P./U.S.P.
Application:
It is used as Anti-adherent and Lubricant in Tablet manufacturing and in Antacid tablets and suspensions formulations.
Specifications:
Test Parameters |
Specification / Limits |
Description | Fine white powder, free from grittiness odorless, slightly hygroscopic |
Solubility | Practically insoluble in water and in ethanol 95 % |
Alkalinity | Complies as I.P./B.P./U.S.P. |
Arsenic | Not more than 4 ppm |
Heavy Metals | Not more than 30 ppm |
Chloride | Note more than 500 ppm |
Sulphate | Not more than 0.5% ppm |
Acid absorption | Not less than 100 ml. of 0.1m Hydrochloric acid required to neutralize 1.0 gm. |
Water soluble salts | Not more than 30 mg per Gm. |
Loss on Ignition | Not less than 17.0% & not more than 34.0% |
Assay As %Mgo | Not less than 29.0% |
Assay As %Sio | Not less than 65.0 |
Magnesium Trisilicate BP
CAS No. : 14987-04-3 Molecular Formula : Mg2Si3O8,xH2OSource : BP-2013
Grades: I.P./B.P./U.S.P.
Application:
It is used as Anti-adherent and Lubricant in Tablet manufacturing and in Antacid tablets and suspensions formulations.
Specifications:
Test Parameters |
Specification / Limits |
Description | Fine white powder, free from grittiness odorless, slightly hygroscopic |
Solubility | Practically insoluble in water and in ethanol 95 % |
Alkalinity | Complies as I.P./B.P./U.S.P. |
Arsenic | Not more than 4 ppm |
Heavy Metals | Not more than 30 ppm |
Chloride | Note more than 500 ppm |
Sulphate | Not more than 0.5% ppm |
Acid absorption | Not less than 100 ml. of 0.1m Hydrochloric acid required to neutralize 1.0 gm. |
Water soluble salts | Not more than 30 mg per Gm. |
Loss on Ignition | Not less than 17.0% & not more than 34.0% |
Assay As %Mgo | Not less than 29.0% |
Assay As %Sio | Not less than 65.0 |